Mycroft leaned back, his body stiff. He was on guard. John had gone around the bend, and he had taken his brother with him. He had a Panic Button on his desk, and with leaning back, it put his hand within easy reach of it. He didn't hit the button yet, but he did subtly look at Anthea. He knew that she was armed and also knew had to hand combat. He also knew that John didn't have his gun, he couldn't have gotten through the metal detectors otherwise. so he didn't fear for his personal safety. He feared for his brother, not that he would admit it.

"No, Doctor Watson. I do not want you to get anywhere close close to me. I want you to leave, right now, without Sherlock. We will get you help."